Morgan Newman Selected Research

Hypoxia (Hypoxemia)

1/2021	No observed effect on brain vasculature of Alzheimer's disease-related mutations in the zebrafish presenilin 1 gene.
11/2020	Accelerated loss of hypoxia response in zebrafish with familial Alzheimer's disease-like mutation of presenilin 1.
1/2016	The Zebrafish Equivalent of Alzheimer's Disease-Associated PRESENILIN Isoform PS2V Regulates Inflammatory and Other Responses to Hypoxic Stress.
7/2015	Alzheimer's disease-related peptide PS2V plays ancient, conserved roles in suppression of the unfolded protein response under hypoxia and stimulation of γ-secretase activity.
10/2014	Hypoxia alters expression of zebrafish microtubule-associated protein tau (mapta, maptb) gene transcripts.
10/2014	Identification and expression analysis of the zebrafish orthologues of the mammalian MAP1LC3 gene family.
1/2013	The Guinea Pig as a Model for Sporadic Alzheimer's Disease (AD): The Impact of Cholesterol Intake on Expression of AD-Related Genes.
1/2012	The BACE1-PSEN-AβPP regulatory axis has an ancient role in response to low oxygen/oxidative stress.
7/2011	The response of HMGA1 to changes in oxygen availability is evolutionarily conserved.

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Morgan Newman Research Topics

Disease

29	Alzheimer Disease (Alzheimer's Disease) 01/2022 - 02/2008
9	Hypoxia (Hypoxemia) 01/2021 - 07/2011
2	Hidradenitis Suppurativa 01/2021 - 02/2014
2	Neurodegenerative Diseases (Neurodegenerative Disease) 03/2018 - 10/2014
1	Genomic Instability 03/2021
1	Iron Deficiencies 01/2021
1	Disease Progression 01/2021
1	Dementia (Dementias) 01/2018
1	Inflammation (Inflammations) 01/2016
1	Stroke (Strokes) 10/2014
1	Brain Ischemia (Cerebral Ischemia) 10/2014
1	Frontotemporal Dementia (Semantic Dementia) 10/2014
1	Pick Disease of the Brain (Pick's Disease) 02/2014
1	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 02/2014
1	Hydrocephalus (Hydrocephaly) 02/2008
1	Neoplasms (Cancer) 02/2008

Drug/Important Bio-Agent (IBA)

9	Proteins (Proteins, Gene)FDA Link 03/2021 - 02/2008
7	Flavin-Adenine Dinucleotide (FAD)IBA 01/2018 - 02/2008
6	Presenilin-2IBA 05/2021 - 01/2018
6	Presenilin-1IBA 01/2021 - 01/2018
6	PresenilinsIBA 01/2021 - 01/2009
4	IronIBA 03/2021 - 01/2018
3	Protein Isoforms (Isoforms)IBA 01/2016 - 10/2014
3	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 01/2016 - 01/2012
2	sortilinIBA 01/2021 - 05/2020
2	Amyloid (Amyloid Fibrils)IBA 04/2019 - 01/2018
2	Amyloid beta-PeptidesIBA 01/2017 - 06/2010
2	CholesterolIBA 01/2016 - 01/2013
2	Sodium AzideIBA 10/2014 - 07/2011
2	diadenosine pyrophosphate (AppA)IBA 02/2014 - 01/2012
1	Apolipoproteins E (ApoE)IBA 01/2022
1	Mutant Proteins (Protein, Mutant)IBA 01/2021
1	ElementsIBA 01/2021
1	3' Untranslated Regions (3' UTR)IBA 01/2021
1	polyglutamineIBA 03/2018
1	CalciumIBA 01/2016
1	CatecholaminesIBA 01/2016
1	MorpholinosIBA 01/2016
1	Peptides (Polypeptides)IBA 07/2015
1	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 10/2014
1	Chloroquine (Aralen)FDA LinkGeneric 10/2014
1	Complement System Proteins (Complement)IBA 01/2014
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2012
1	CatalaseIBA 01/2012
1	Messenger RNA (mRNA)IBA 01/2012
1	F2-Isoprostanes (F2 Isoprostanes)IBA 01/2012
1	Arachidonic Acid (Vitamin F)IBA 01/2012
1	SuspensionsIBA 07/2011